The best replacement for .22 wmr is .17 hmr.

The best alternatives to .22 wmr are rated as following:
★★★★★  .17 hmr
★★★★  .22 mag
★★★  .22lr
★★★  .22 magnum
★★  .17
★  .32 acp
★  .22 lr
★  .22 hornet
  .38 special
  lr
  marlin .22 wmr
  .22 wrf

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.22 wmr
.17 hmr
.22 mag