The best replacement for whole blood is plasma.

The best alternatives to whole blood are rated as following:
★★★★★  plasma
★★★  serum
★★★  plasma glucose
★★  packed red blood cells
★★  packed cells
★★  double red
★  double red cells
★  platelets
★  platelet donation
★  prbc
★  pbmc
★  red cells
★  blood plasma
★  plasma blood
  double red cell
  packed blood
  serum glucose
  peripheral blood
  apheresis
  stored whole blood
  plasma donation
  packed cell
  blood serum
  packed red cells
  red blood cells
  serum blood
  platelets donation
  ffp

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Google Trends

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whole blood
plasma
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