The best replacement for vxworks is qnx.

The best alternatives to vxworks are rated as following:
★★★★★  qnx
★★★★  integrity
★★★  rtlinux
★★★  lynxos
★★  windows ce
★★  freertos
★★  nucleus
★★  embedded linux
★  threadx
★  ecos
★  rtems
  wince
  wind river linux
  greenhills
  win ce

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vxworks
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integrity