The best replacement for vpx is vme.

The best alternatives to vpx are rated as following:
★★★★★  vme
★★★  cpci
★★  mpx
★★  openvpx
★  atca
★  vxs
★  isopure

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Google Trends

Scale is based on the average worldwide traffic of vpx in all years. Click on graph for more.
vpx
vme
cpci