The best replacement for u5 is u4.

The best alternatives to u5 are rated as following:
★★★★★  u4
★★★  denial
★★★  ibp
★★★  u3
★★★  reddi
★★★  skdc
★★  u8
★★  radial jdi
★  focusrite isa one
★  u5i

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No companions for u5 have been suggested so far.
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Google Trends

Scale is based on the average worldwide traffic of u5 in all years. Click on graph for more.
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