The best replacement for thalassemia is sickle cell.

The best alternatives to thalassemia are rated as following:
★★★★★  sickle cell
★★★★★  iron deficiency anemia
★★★  sickle cell anemia
★★★  iron deficiency
★★  anemia
★★  beta thalassemia
★  sickle cell disease
★  g6pd
★  sideroblastic anemia
★  ida
  other congenital anemia
  spherocytosis
  sickle beta zero thalassemia
  cooley\u0027s anemia
  cooley anemia
  sickle cell trait
  sickle trait
  cooley's anemia

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Speaking about thalassemia, one probably shouldn't forget about high rbc.

Other search terms related to thalassemia and their ratings are:
★★★★★ high rbc
★★★★ iron deficiency
★★★★ iron overload
★★★★ sickle cell trait
★★★★ sickle cell
★ hemoglobin c
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thalassemia
sickle cell
iron deficiency anemia