The best replacement for tagamet is zantac.

The best alternatives to tagamet are rated as following:
★★★★★  zantac
★★★★  prilosec
★★★★  pepcid
★★  nexium
★  prevacid
★  ranitidine
  protonix
  pepcid ac
  grapefruit juice
  cimetidine
  otc tagamet
  tagamet hb

Your alternative for tagamet is not listed? Suggest!
Speaking about tagamet, one probably shouldn't forget about loperamide.

Other search terms related to tagamet and their ratings are:
★★★★★ loperamide
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Google Trends

Scale is based on the average worldwide traffic of tagamet in all years. Click on graph for more.
tagamet
zantac
prilosec