The best replacement for supersix is synapse.

The best alternatives to supersix are rated as following:
★★★★★  synapse
★★★★★  tarmac
★★★★  madone
★★★★  caad10
★★★  supersix evo
★★★  caad
★★  synapse carbon
★★  tcr advanced
★★  r3
★  supersix
★  tcr
★  system six
★  trek madone
★  hi mod
★  six13
★  specialized tarmac
  caad 10
  caad9
  scott cr1
  cervelo r3

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supersix
synapse
tarmac