The best replacement for superman prime is galactus.

The best alternatives to superman prime are rated as following:
★★★★★  galactus
★★★★  silver surfer
★★★★  thanos
★  rune king thor
★  superboy prime
★  odin
★  world war hulk
★  sentry
★  ssj4 goku
  ion
  dr manhattan
  monarch
  superman one million
  silver age superman
  super saiyan god
  dark phoenix

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superman prime
galactus
silver surfer