The best replacement for scepter is void staff.

The best alternatives to scepter are rated as following:
★★★★★  void staff
★★★★  sceptre
★★★  sword mesmer
★★★  staff elementalist
★★★  deathcap
★★★  lci
★★★  staff gw2
★★  renewing stamina
★★  athene's unholy grail
★  doran's blade
★  haunting guise
  rabadon's

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Speaking about scepter, one probably shouldn't forget about overload.

Other search terms related to scepter and their ratings are:
★★★★★ overload
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scepter
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