The best replacement for proton pump inhibitor is h2 blocker.

The best alternatives to proton pump inhibitor are rated as following:

★★★★★	h2 blocker
★★	h2 antagonist
	histamine 2 receptor antagonist
	antagonist
	ppi

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Speaking about proton pump inhibitor, one probably shouldn't forget about nsaid.

Other search terms related to proton pump inhibitor and their ratings are:

★★★★★

nsaid

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proton pump inhibitor

h2 blocker

h2 antagonist