The best replacement for panamera is m5.

The best alternatives to panamera are rated as following:
★★★★★  m5
★★★★  911
★★★  panamera s
★★★  rapide
★★★  quattroporte
★★★  tesla
★★  a7
★★  ghibli
★★  s class
★★  panamera 4
★★  cayenne
★★  maserati
★★  model s
★★  aston martin rapide
★★  rs7
★  cts-v
★  macan
★  audi a7
★  cls
★  bmw 7 series
★  maserati quattroporte
  a8
  carrera
  bmw m5
  audi a8
  mercedes s class
  audi rs6

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Google Trends

Scale is based on the average worldwide traffic of panamera in all years. Click on graph for more.
panamera
m5
911