The best replacement for orlistat is sibutramine.

The best alternatives to orlistat are rated as following:
★★★★★  sibutramine
★★★★★  alli
★★★★  phentermine
★★★  xenical
★★★  chitosan
★  cetilistat
★  xls medical
★  litramine
★  reductil
  xls
  metformin
  olestra
  rimonabant

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No companions for orlistat have been suggested so far.
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Google Trends

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orlistat
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