The best replacement for northern blot is southern blot.

The best alternatives to northern blot are rated as following:
★★★★★  southern blot
★★★  western blot
★★★  microarray
★★★  rt-pcr
★★  qpcr
★  rt pcr
★  real time pcr
  southern
  qrt-pcr

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northern blot
southern blot
western blot