The best replacement for nephew is cousin.

The best alternatives to nephew are rated as following:
★★★★★  cousin
★★★★  grand nephew
★★★★  niece
★★★  great nephew
★★  aunt
★  cousin difference
★  dynasty
★  timbaland
★  second cousin
★  nice
★  arthrex
★  hologic
★  grandnephew
  neice
  neise
  uncle

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Speaking about nephew, one probably shouldn't forget about aunt.

Other search terms related to nephew and their ratings are:
★★★★★ aunt
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nephew
cousin
grand nephew