The best replacement for multifilament is poly.

The best alternatives to multifilament are rated as following:
★★★★★  poly
★★★★★  monofilament
★★★  synthetic gut
★  monofilament sutures
★  synthetc gut
  natural gut
  monofilament suture

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Google Trends

Scale is based on the average worldwide traffic of multifilament in all years. Click on graph for more.
multifilament
poly
monofilament