The best replacement for mbox 3 pro is digi 003.

The best alternatives to mbox 3 pro are rated as following:
★★★★★  digi 003
★★★★  mbox 3
★★★  apogee duet 2
★★  rme babyface
★  mbox 2 pro
  003
  profire 2626

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mbox 3 pro
digi 003
mbox 3