The best replacement for mbox 1 is mbox 2.

The best alternatives to mbox 1 are rated as following:
★★★★★  mbox 2

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Speaking about mbox 1, one probably shouldn't forget about pro tools 8.

Other search terms related to mbox 1 and their ratings are:
★★★★★ pro tools 8
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mbox 1
mbox 2