The best replacement for logitech z506 is klipsch promedia 2.1.

The best alternatives to logitech z506 are rated as following:
★★★★★  klipsch promedia 2.1
★★★★★  bose companion 2
★★★★  cyber acoustics ca-5402
★★★★  creative inspire t6300
★★★★  creative t6300
★★★  creative t6160
★★★  creative a550
★★  edifier m1550
★★  iball booster
★  creative inspire t6160
★  f&d f6000
★  edifier m3500
  creative t6100

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logitech z506
klipsch promedia 2.1
bose companion 2