The best replacement for lexus is is es.

The best alternatives to lexus is are rated as following:
★★★★★  es
★★★★  acura tl
★★★  bmw 3
★★★  bmw 3 series
★★  acura tsx
★  infiniti g35
★  cadillac ats
★  infiniti g
★  mercedes c class
★  lexus es
★  mercedes cla
  c class
  infiniti q50
  3 series
  bmw 328i
  2006 bmw 3 series
  mercedes c
  mercedes c-class

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lexus is
acura tl