The best replacement for istanbul is constantinople.

The best alternatives to istanbul are rated as following:
★★★★★  constantinople
★★★  ankara
★★★  athens
★★  budapest
★★  cairo
★★  prague
★★  istambul
★  nehalem
★  dubai
★  antalya
★  blanket
★  marrakech
★  morocco
  izmir
  greece
  jscoverage
  bosphorus
  recordmydesktop
  tehran
  marrakesh

Your alternative for istanbul is not listed? Suggest!
Speaking about istanbul, one probably shouldn't forget about ankara.

Other search terms related to istanbul and their ratings are:
★★★★★ ankara
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Google Trends

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istanbul
constantinople
ankara