The best replacement for isolationism is internationalism.

The best alternatives to isolationism are rated as following:
★★★★★  internationalism
★★★★  interventionism
★★★  imperialism
★★  intervention
★★  expansionism
★  non interventionism
★  non-interventionism
★  globalization
  non interventionist
  involvement
  expansion
  non intervention
  internationalism interventionism
  interventionist

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Google Trends

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isolationism
internationalism
interventionism