The best replacement for htc desire is samsung mesmerize.

The best alternatives to htc desire are rated as following:
★★★★★  samsung mesmerize
★★★★  samsung galaxy s
★★★★  htc one
★★★  nexus one
★★  motorola milestone
★★  wildfire
★★  samsung galaxy s3
★  htc evo 3d
★  virgin mobile supreme
★  htc wildfire
★  htc evo
★  htc hero
★  htc inspire
★  htc incredible
★  zte supreme
★  htc legend
★  sony xperia sp
★  htc hd2
★  samsung galaxy victory
★  mesmerize
★  htc desire hd
  galaxy s
  iphone 3gs
  htc touch pro 2
  hd2
  one v
  apple iphone
  desire hd
  merge
  legend
  xperia x10
  samsung galaxy
  nexus s
  samsung acclaim

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Speaking about htc desire, one probably shouldn't forget about htc sense.

Other search terms related to htc desire and their ratings are:
★★★★★ htc sense
★★ android 2.3
★★ new htc sense
★★ ics
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htc desire
samsung mesmerize
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