The best replacement for hplc is gc.

The best alternatives to hplc are rated as following:
★★★★★  gc
★★★★  fplc
★★  uplc
★★  ce
★★  lc
★★  tlc
★  gas chromatography
★  lcms
★  mass spectrometry
★  gc ms
★  column chromatography
★  uhplc
★  ic
★  hplc
★  mass spec
  lc ms
  elisa
  electrophoresis
  liquid chromatography
  reverse phase hplc
  capillary electrophoresis
  uv spectroscopy
  nmr
  glc
  ftir
  gcms
  ion chromatography

Your alternative for hplc is not listed? Suggest!
Speaking about hplc, one probably shouldn't forget about electrochemical detection.

Other search terms related to hplc and their ratings are:
★★★★★ electrochemical detection
★★★ uv detection
★★ fluorescence detector
★★ ri detector
★ uv detector
You have in mind a companion for hplc and it is not yet here? Propose!



Google Trends

Scale is based on the average worldwide traffic of hplc in all years. Click on graph for more.
hplc
gc
fplc