The best replacement for hl7 is edi.

The best alternatives to hl7 are rated as following:
★★★★★  edi
★★★★★  x12
★★★★  dicom
★★★  hipaa
★★  xml
★★  astm
★  openehr
★  ihe
  ncpdp
  cdisc

Your alternative for hl7 is not listed? Suggest!
Speaking about hl7, one probably shouldn't forget about cda.

Other search terms related to hl7 and their ratings are:
★★★★★ cda
★ embedded pdf
You have in mind a companion for hl7 and it is not yet here? Propose!



Google Trends

Scale is based on the average worldwide traffic of hl7 in all years. Click on graph for more.
hl7
edi
x12