The best replacement for high fructose corn syrup is sugar.

The best alternatives to high fructose corn syrup are rated as following:
★★★★★  sugar
★★★★★  corn syrup
★★★  cane sugar
★★★  sucrose
★★  fructose
★  aspartame
★  table sugar
★  sugar cane
★  sucralose
★  corn syrup solids
★  natural sugar
  regular corn syrup
  brown rice syrup
  agave
  crystalline fructose
  high maltose corn syrup
  pure cane sugar
  cane juice
  corn sugar
  agave nectar
  fructose syrup
  real sugar

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No companions for high fructose corn syrup have been suggested so far.
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Google Trends

Scale is based on the average worldwide traffic of high fructose corn syrup in all years. Click on graph for more.
high fructose corn syrup
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