The best replacement for hexproof is shroud.

The best alternatives to hexproof are rated as following:
★★★★★  shroud
★★★★★  deathtouch
★★★★  supreme verdict
★★★  counter
★★★  infect
★★★  planeswalkers
★★★  enchantment
★★★  destroy all
★★★  overload
★★  abilities
★★  exile
★★  protection
★★  shroud mtg
★  wrath of god
★  anger of the gods
  sacrifice
  creature abilities

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Speaking about hexproof, one probably shouldn't forget about enchantments.

Other search terms related to hexproof and their ratings are:
★★★★★ enchantments
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Google Trends

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hexproof
shroud
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