The best replacement for hd 6450 is hd 5450.

The best alternatives to hd 6450 are rated as following:
★★★★★  hd 5450
★★★★★  gt 610
★★★★  gt 630
★★★★  hd 6570
★★★  gt 620
★★  gt 520
★  gt 420
★  gt 240
★  hd 6670
★  geforce 210
★  9500gt
★  hd 4200
★  hd 5570
★  5450
  hd 5670

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hd 6450
hd 5450
gt 610