The best replacement for give up is give in.

The best alternatives to give up are rated as following:
★★★★★  give in
★★★  find luke and kenny
★★★  keep trying
★★★  try harder
★★★  die trying
★★  step out
★  gave up
★  surrender
  cmta
  quit
  let go
  give up on

Your alternative for give up is not listed? Suggest!
Speaking about give up, one probably shouldn't forget about such a wonderful life.

Other search terms related to give up and their ratings are:
★★★★★ such a wonderful life
★ lyrics by yolanda adams
You have in mind a companion for give up and it is not yet here? Propose!



Google Trends

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give up
give in
find luke and kenny