The best replacement for framemaker is word.

The best alternatives to framemaker are rated as following:
★★★★★  word
★★★★  indesign
★★  pagemaker
★★  robohelp
★★  structured framemaker
★★  microsoft word
★★  arbortext
★  flare
★  ms word
★  scribus
★  quark
★  quarkxpress
  xmetal
  madcap flare
  unstructured framemaker

Your alternative for framemaker is not listed? Suggest!
Speaking about framemaker, one probably shouldn't forget about robohelp.

Other search terms related to framemaker and their ratings are:
★★★★★ robohelp
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Google Trends

Scale is based on the average worldwide traffic of framemaker in all years. Click on graph for more.
framemaker
word
indesign