The best replacement for endemic is epidemic.

The best alternatives to endemic are rated as following:
★★★★★  epidemic
★★★★  indigenous
★★★  pandemic
★★  systemic
★★  native
★  non endemic
★  exotic
★  cosmopolitan
★  hyperendemic
  sporadic
  epidemic malaria
  non-endemic
  enzootic

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No companions for endemic have been suggested so far.
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Google Trends

Scale is based on the average worldwide traffic of endemic in all years. Click on graph for more.
endemic
epidemic
indigenous