The best replacement for datto is axcient.

The best alternatives to datto are rated as following:
★★★★★  axcient
★★★★★  unitrends
★★★★  appassure
★★★★  storagecraft
★★★  evault
★★  efolder
★  doyenz
★  asigra
★  intronis

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Google Trends

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datto
axcient
unitrends