The best replacement for colonization is infection.

The best alternatives to colonization are rated as following:
★★★★★  infection
★★★★  immigration
★★★★  imperialism
★★★  globalization
★★  colonialism
★★  english colonization
★★  colonisation
★  occupation
★  conquest
★  spanish colonization
★  contamination
  infection mrsa
  freecol
  exploration
  decolonization
  beyond the sword

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No companions for colonization have been suggested so far.
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Google Trends

Scale is based on the average worldwide traffic of colonization in all years. Click on graph for more.
colonization
infection
immigration