The best replacement for chemiluminescence is fluorescence.

The best alternatives to chemiluminescence are rated as following:
★★★★★  fluorescence
★★★  elisa
★★  colorimetric
★★  electrochemiluminescence
★★  fluorescence western blot
★  chromogenic
  bioluminescence

Your alternative for chemiluminescence is not listed? Suggest!
Speaking about chemiluminescence, one probably shouldn't forget about luminol.

Other search terms related to chemiluminescence and their ratings are:
★★★★★ luminol
You have in mind a companion for chemiluminescence and it is not yet here? Propose!



Google Trends

Scale is based on the average worldwide traffic of chemiluminescence in all years. Click on graph for more.
chemiluminescence
fluorescence
elisa