The best replacement for blessing is curse.

The best alternatives to blessing are rated as following:
★★★★★  curse
★★★★  blessings
★★★  lesson
★★  birthright
★★  luck
★★  bane
★  miracle
★  baptism
★  cursing
★  blasphemy
★  favor
★  original sin
★  benefit
  blight
  christening
  grace
  claw hand
  prayer
  curse derek prince

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Speaking about blessing, one probably shouldn't forget about curse.

Other search terms related to blessing and their ratings are:
★★★★★ curse
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