The best replacement for biocube is red sea max.

The best alternatives to biocube are rated as following:
★★★★★  red sea max
★★★★★  nano cube
★★★  aquapod
★★★  nuvo
★★  jbj
★★  jbj nano cube
★★  hqi
★★  fluval edge
★  innovative marine
  oceanic biocube
  red sea
  nanocube

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Google Trends

Scale is based on the average worldwide traffic of biocube in all years. Click on graph for more.
biocube
red sea max
nano cube