The best replacement for 780 sli is 780 ti.

The best alternatives to 780 sli are rated as following:
★★★★★  780 ti
★★★  770 sli
★★★  690
★★★  titan black
★★  gtx 690
★★  290 crossfire
★  290x crossfire
★  gtx 780 ti sli
★  gtx 780 ti
★  680 sli
★  gtx 680 sli
★  7990
  7970 crossfire
  gtx 790

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780 sli
780 ti
770 sli