The best replacement for 5850 is 6850.

The best alternatives to 5850 are rated as following:
★★★★★  6850
★★★★★  5870
★★★★★  7850
★★★★  6870
★★★  5770
★★★  7870
★★★  7770
★★  6950
★★  7750
★★  560 ti
★  7790
★  gtx 460
★  460
★  6770
★  550 ti
★  4890
★  gtx 470
★  gtx 285
★  570
  gtx 275
  470
  hd 6850
  285
  4870
  crossfire
  hd 6870
  275
  gtx 560 ti

Your alternative for 5850 is not listed? Suggest!
Speaking about 5850, one probably shouldn't forget about 5870.

Other search terms related to 5850 and their ratings are:
★★★★★ 5870
★★★★★ 5870 crossfire
★★★ 5830
★★ 6870
★★ 5970
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Google Trends

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5850
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