The best replacement for 4650 is 5450.

The best alternatives to 4650 are rated as following:
★★★★★  5450
★★★★  5570
★★★★  4670
★★★★  6450
★★★  9500gt
★★  9600gt
★★  gt220
★★  3850
★  9500
★  3650
★  3870
★  gt 220
★  1gb nvidia geforce gt 220
  nvidia geforce gt 220
  9600
  hd 6450
  9600m gt
  hd 3650
  9500 gt
  geforce 9600m gt

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4650
5450
5570