The best replacement for 45 colt is 45 acp.

The best alternatives to 45 colt are rated as following:
★★★★★  45 acp
★★★★  45 long colt
★★★★  44 mag
★★★  357
★★★  44 magnum
★★  357 mag
★★  44 special
★★  long colt
★★  357 magnum
★★  454 casull
★  45-70
★  45 auto
★  38 special
★  44-40
  357 recoil
  44 40
  44 mag ballistics
  30-30
  41 mag
  410
  .45 long colt
  45 schofield
  .357 mag
  45 lc
  acp
  45lc
  410 slug
  45 70
  44\/40
  45 long colt ammo
  .357

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45 colt
45 acp
45 long colt