The best replacement for 2x10 is 1x11.

The best alternatives to 2x10 are rated as following:
★★★★★  1x11
★★★★★  3x10
★★★★★  1x15
★★★★★  3x9
★★★★★  1x12
★★★★  1x10
★★★  2x12
★★★  3x10 29er
★★  1x15 bass cab
★  4x10
★  1x15 bass amp
★  i joist
★  2x12 bass cab
★  1x15 bass
★  2x12 cab
  2x9
  3x8
  sram 2x10
  joist
  lvl

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2x10
1x11
3x10