The best replacement for 25 06 is 270.

The best alternatives to 25 06 are rated as following:
★★★★★  270
★★★★★  243
★★★★  7mm 08
★★★★  30 06
★★★  308
★★  257 weatherby
★★  22 250
★  260
★  22 250 ballistics
★  .308
  257 weatherby mag
  6mm
  6.5x55
  257 roberts
  25 wssm
  257
  25 06 ai
  7-08
  .270

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25 06
270
243